i used boric acid suppositories while pregnantUncategorized

When this is not enough, artificial lubricants or, Vaginal infections can cause some uncomfortable symptoms. Keep boric acid out of the reach of children. Learn more, Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. It may be best to use vaginal suppositories before going to bed. How to use boric acid suppositories It's a homeopathic prescription medicine that contains probiotics, as well as vitamin C or E for protection against free radicals in the body (from sunlight). Epub 2006 Mar 10. The alternatives include 14 days of intravaginal treatment with a boric acid gelatin capsule, nystatin suppository, 17% flucytosine cream, or a cream with 17% flucytosine and 3% amphotericin B. Good luck to you. However if you've been TTC for 15 months, I recommend you see a reproductive endocrinologist for testing and possible treatment. While the research on boric acid for BV is limited, doctors sometimes recommend boric acid suppositories to treat people who get repeated infections. Boric acid addition to suppressive antimicrobial therapy for recurrent bacterial vaginosis. Into astrology? The researchers concluded that with all the available research, boric acid is a safe alternative to other treatments. Boric Acid For Bv While Pregnant | FollowMDA Boric acid can be used for other purposes . If you experience severe discomfort, discontinue use. Bacterial vaginosis and yeast infections can cause similar symptoms, but they require different treatments. A 2003 study examined the use of suppositories for 2 weeks versus 3 weeks. I feel like the boric acid has helped in the past, I just worry about using if I'm pregnant and don't know it yet, like during the two week wait. Keep boric acid out of the reach of children. Sexually Transmitted Diseases. But that doesn't mean you should use an over-the-counter (OTC) boric acid product without talking to your doctor first. The Killer boric acid suppository. She is also a 10-time marathoner, frequent traveler and avid amateur baker. Here is how to treat and help prevent. Boric acid suppositories take only a few minutes to completely dissolve in the vagina. At times, boric acid suppositories work more effectively than . Its caused by an imbalance of natural pH in your vagina. Wearing sanitary pads will protect underwear and bed linen from leakage. Reichman, Orna, et al. Can Boric Acid Help Treat Bacterial Vaginosis? What is boric acid used for vaginally? (n.d.). You may wish to wear a panty liner to protect your clothing from discharge from the suppository. 12 Reasons Your Vagina Hurts So Damn Much, The Best Cleansers For Avoiding Vaginal Irritation, 16 Best Natural Lubes, According To Gynecologists, These Bidets Will Keep Your Butt Happier Than Ever, From Women's Health for Urovant Sciences and GEMTESA, Your Privacy Choices: Opt Out of Sale/Targeted Ads. Consider wearing a panty liner, as there may be discharge after you insert the suppository. This is because it can be toxic if ingested orally. A recent clinical trial suggested that hormonal suppositories might be an effective treatment for vaginal dryness, particularly among women who are unable to take Hormone Replacement Therapy (HRT). Both treatments offered significant improvement in symptoms after 4 weeks, although the estrogen cream was the most effective. Clinicians use of intravaginal boric acid maintenance therapy for recurrent vulvovaginal candidiasis and bacterial vaginosis. Even though BV is the most common vaginal infection, the exact cause isn't understood beyond bacteria overgrowth. V-Bella boric acid suppository. Many people find it convenient to insert it before going to bed. Boric acid suppositories are not safe to use in the period of pregnancy. Vaginal suppositories for contraception tend to be less effective than more common methods of birth control. Boric acid suppositories are not safe to use in the period of pregnancy. If the baby does survive the pregnancy and birth, exposure to boric acid will likely lead to significant birth defects, including heart defects and abnormalities of the body structure, such as abnormal ribs and missing vertebrae. Boric Acid for Bacterial Vaginosis and Other Home Remedies - Healthline , Doctor Medical Verified Dr. Hasan, Doctor 23,209 Satisfied Customers MBBS, FCPS, with experience in all fields of medicine and surgery Dr. Hasan is online now Related Medical Questions Can u take boric acid capsules if you have high blood Dr. Owen : Well the truth is that there is no data to support that at all Dr. Owen : So, it is very Unlikely to cause any birth defect Dr. Owen : Boric acid is just a neutralizer to help with yeast infections Dr. Owen : So, not necessarily dangerous. It is probably a side effect of long term use of boric acid. People can take vaginal suppositories during a menstrual period. A person should take the medication for as long as directed, even if the symptoms go away. Copyright 2023 Leaf Group Ltd. / Leaf Group Media, All Rights Reserved. But when used by mouth (internally), on open wounds, or by children, boric acid is toxic. A 2019 study looked at the effectiveness of boric acid for recurrent yeast infections. This article provides a step-by-step guide on how to use vaginal suppositories. Before inserting a boric acid vaginal suppository, wash and dry your hands. If you buy through links on this page, we may earn a small commission Heres our process. (2019). But research on how effective boric acid is in treating BV is still limited. Medical News Today only shows you brands and products that we stand behind. A study done by Boston University Medical Center found that human mothers who used boric acid medications during their pregnancies were almost two times as likely to give birth to children with major birth defects. I'm not familiar with boric acid or its purpose. After you've finished the original course of treatment recommended by your doctor, there are many regimens you can implement that involve these suppositories to prevent a recurrent infection. Topical corticosteroids can be used for symptomatic relief. The natural form of this compound is found in volcanic areas in Europe and North America and has been used at least since the time of the ancient Greeks for cleaning, preserving food, and other purposes. Vaginal boric acid may also be used for purposes not listed in this medication guide. (2019). Unlikely. As an acid, it may also help maintain normal pH of the vagina when prescribed by a health care provider. ---------------Siggy Warning--------------------. Her areas of expertise include fibroids, irregular vaginal bleeding, abnormal pap smears, infertility and menopause. It found that boric acid suppositories were effective in managing recurrent yeast infections with minimal side effects. 5 Non-Christmas Movies to Watch This Holiday, Best Online Games to Play with your Friends, 12 tips for creating visual content on social media. A more recent 2018 laboratory study found that boric acid works by restricting the growth of Candida albicans and Candida glabrata strains that have become resistant to conventional drug treatment. Our team thoroughly researches and evaluates the recommendations we make on our site. DOI: Boric acid safe for chronic yeast infections? Can poor sleep impact your weight loss goals? If ingested, borates will cause severe internal bleeding or even death in some cases! There was little to no difference in outcome with the longer treatment duration. Treatment of vaginitis caused by Candida glabrata: use of topical boric acid and flucytosine. Its likely youll notice that boric acid suppositories are marketed as a homeopathic product. Here are 7 of the best over-the-counter yeast infection pills, creams, gels, and treatments. Not only is it antiviral and antifungal, but it also works to treat both Candida albicans and the more resistant Candida glabrata yeast strains. Sorry you're dealing with this. This content is imported from poll. I have read mixed reviews on other chat boards about how there are dangers to using boric acid during pregnancy, and some resulted in miscarriage. You may have other remedies at home, waiting to be used. They should be placed in the vagina nightly before bed for two weeks, or as recommended by your healthcare provider. Bacterial Vaginosis CDC Basic Fact Sheet. Learn to tell the two apart and more here. Antifungal Mechanisms Supporting Boric Acid Therapy of Candida Vaginitis. Journal of Antimicrobial Chemotherapy, vol. Is that what you meant when you said your taking probiotics? Agency for Toxic Substances and Disease Registry. For potential or actual medical emergencies, immediately call 911 or your local emergency service. How Boric Acid Treats Bacterial Vaginosis, 7 Reasons Why It Hurts to Peeand What To Do About It, 5 Things That Can Change the Way Your Vagina Smells, Why Does Sex Have a Smell? Yeast infection. Boric acid suppositories are sometimes prescribed as an alternative treatment for vaginal yeast infections that keep occurring despite treatment. Can diet help improve depression symptoms? Can You Use Boric Acid for a Yeast Infection? - Healthline Iavazzo, C., Gkegkes, I. D., Zarkada, I. M., & Falagas, M. E. (2011, August). Here are some important restrictions to keep in mind: Find out what you can do with our Health Assistant, Yeast Infection (Vaginal). Mayo Clinic, Mayo Foundation for Medical Education and Research, 16 July 2019, www.mayoclinic.org/diseases-conditions/yeast-infection/diagnosis-treatment/drc-20379004. Possible side effects for its use in yeast infections include burning, discharge, or redness. They result from an increased growth of yeast in the vagina, which causes irritation, swelling, and itching in the area. It can be formulated in vaginal capsules, but theyre meant only for intravaginal insertion (meaning you put the capsule directly in the vagina) and should never be taken orally. Over 12 weeks, 325 women took a hormonal suppository called Prasterone, and 157 women took a placebo. sciencedirect.com/science/article/abs/pii/S0959652613006896, journals.lww.com/stdjournal/fulltext/2017/02000/trichomonas_vaginalis_treated_with_boric_acid_in_a.12.aspx, link.springer.com/article/10.1007/s00204-020-02700-x, goaskalice.columbia.edu/answered-questions/boric-acid-safe-chronic-yeast-infections, ods.od.nih.gov/factsheets/Boron-HealthProfessional/, ncbi.nlm.nih.gov/pmc/articles/PMC4518586/, npic.orst.edu/factsheets/archive/borictech.html, fda.gov/drugs/information-drug-class/homeopathic-products, ncbi.nlm.nih.gov/pmc/articles/PMC6376090/, ncbi.nlm.nih.gov/pmc/articles/PMC4514959/, ncbi.nlm.nih.gov/pmc/articles/PMC6878170/, journals.lww.com/stdjournal/Fulltext/2009/11000/Boric_Acid_Addition_to_Suppressive_Antimicrobial.13.aspx, dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4d8aeba0-4848-4093-a723-1db50301d025, wwwn.cdc.gov/TSP/ToxFAQs/ToxFAQsDetails.aspx?faqid=452&toxid=80, dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3c3a423c-805d-4146-b16e-0138617a8dc6. Who should not use boric acid suppositories? Boric Acid Suppositories While Pregnant | Www.eplifefit.com Avoid having vaginal intercourse while youre using boric acid suppositories. Check with your doctor about alternative trea before having intercourse. In some cases, boric acid suppositories might be prescribed as an alternative treatment, although their effectiveness and safety have not been fully studied. Get weekly updates on baby and your body. Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT. It can be helpful to lie down with your knees bent or slightly squatting. Why are you using that for so long anyways? Boric acid should not be used during pregnancy its toxic to the developing fetus. Be sure to insert the suppository at the same time each day. Boric acid is used for a variety of reasons, including pharmaceutical and agricultural, among others. But if the balance of normal vaginal bacteria and yeast changes, symptoms of candidiasis can arise. Can you use suppositories while pregnant? Can I use a tampon while AZO Boric Acid? What Happens If I Used Boric Acid While Pregnant Boric Acid Vaginal Suppositories: Everything You Need to Know There are other options available, like topical flucytosine (Ancobon), that also target this more resistant yeast. (n.d.). Falagas, M E, et al. Unlock the power of information, anytime, anywhere. Renita White, MD, is an obstetrician/gynecologist at Georgia Obstetrics and Gynecology in Atlanta, Georgia. Get prescriptions or refills through a video chat, if the doctor feels the prescriptions are medically appropriate. While boric acid is traditionally used as roach poison, boric acid suppositories are safe to use vaginally. Typical symptoms include genital itching, a green or yellow foul-smelling vaginal discharge, and pain when urinating and during sex. Safely nursing after using boric acid post - What to Expect For women who are sensitive to hormone therapy, vitamin E suppositories could potentially be a suitable and safer alternative. Vaginal dryness can affect people of any age but is more common among those transitioning to menopause. 2005-2023 Healthline Media a Red Ventures Company. Can I use PH suppositories while pregnant? Research into boric acid for bacterial vaginosis is more limited. VeeCleanse Boric Acid Suppositories - VeeFresh Clinicians strongly advise against the oral consumption of boric acid. Can i have sex while using boric acid suppositories? This is much more than the amount of boric acid thats in a boric acid suppository, which is typically 600 milligrams. Using your fingers or an applicator specifically designed for this purpose, gently insert the suppository into your vagina as far as it will comfortably go. Can boric acid stop your period? - qyvxl.dixiesewing.com Can I have sex while using boric acid suppositories? If you experience any discomfort or side effects, make sure to contact a health care provider right away. (2015). used boric acid to clear up my yi, which it did. It is used in various prescription pharmaceutical products and is also available without a prescription. You may have heard that you can become very sick or potentially die from boric acid. The health risks associated with boric acid during pregnancy are quite significant, and it should be avoided as much as possible. Reichman O, et al. Diluted boric acid may be used to treat skin conditions like diaper rash, insect bites, athletes foot, foot odor, and yeast infections. Healthline Media does not provide medical advice, diagnosis, or treatment. Her work has appeared in publications like SELF, Greatist, and PureWow. Can i use boric acid suppositories while pregnant? - Dane101 Heres what you need to know and when you should contact your doctor. I've never heard of using boric acid for that, so I'm not really any help there. Boric acid for recurrent vaginal yeast infections. No serious or severe side effects were observed. 12/13 IVF #2 = November / December 2013. Many women have found that boric acid is an effective treatment for their yeast infections. How can I fix my pH balance during pregnancy? They act only locally so there is no transfer to the bloodstream and thus to t. Read More Created for people with ongoing healthcare needs but benefits everyone. It's also important to stow suppositories out of the reach of children because boric acid can be fatal if consumed orally. Vaginal yeast infections are associated with the candida genus of yeast, which is normally always in the vagina, just in much lower numbers. He or she will also probably be able to tell you about the boric acid. Research suggests that boric acid restricts the growth of both C. albicans and C . Often, mild yeast infections can be treated with over-the-counter medications. A: Our spray is made with Amezol, a remarkable compound made up of natural peptide and amino acid derivatives that uniquely and safely neutralizes odor. "And many daily practices or infections can disrupt this pH and cause symptoms such as itching, irritating, odor, abnormal discharge, and infection with yeast or other bacterial overgrowth.. Hamilton RA, et al. You may see some improvement in as little as one day, but its important to complete the full course of medication to ensure that the infection doesnt return. If left untreated, a yeast infection may lead to health problems, such as invasive, Can you have sex with a yeast infection? No serious side effects or deaths have been reported. To establish that the product manufacturers addressed safety and efficacy standards, we: We do the research so you can find trusted products for your health and wellness. Life cycle environmental impact assessment of borax and boric acid production in China. Use a dinner knife to remove any excess powder from the top and close the capsule tightly. However, studies in humans havent returned the same results. Boric acid suppositories are a safe and effective way to treat vaginal yeast infections. (2014). Boric Acid Suppositories for Vaginal Health - Verywell Health Even the highest levels of environmental boron exposure were too low to reach blood and tissue levels that would have harmful effects on human reproduction. Is boric acid safe to use while pregnant? (2016, March). Boric Acid Suppositories While Pregnant Boric acid shouldn't be used during pregnancy because it can harm the developing fetus. To treat BV, the boric acid capsules can be inserted into the vagina at night for about 1-2 weeks. Boric acid is a chemical thats been used to treat some types of vaginal infections. I also try to use only fragrance free. Before you try boric acid suppositories, make an appointment with your healthcare professional to get a diagnosis. Vaginal boric acid may also be used for purposes not listed in this medication guide. Lastly, you should always obtain these capsules from a reputable pharmacy, Dr. Dweck says. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, Using vaginal suppositories: Step-by-step, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114791/, https://www.plannedparenthood.org/learn/birth-control/spermicide/how-do-i-use-spermicide, https://www.plannedparenthood.org/learn/birth-control/spermicide/how-effective-spermicide, https://www.liebertpub.com/doi/abs/10.1089/jwh.2010.2708, https://journals.lww.com/menopausejournal/Abstract/2016/03000/Efficacy_of_intravaginal_dehydroepiandrosterone.6.aspx, https://link.springer.com/article/10.1007/s11046-017-0209-6, https://www.cdc.gov/fungal/diseases/candidiasis/genital/index.html, https://www.cdc.gov/std/tg2015/candidiasis.htm. Try these tips to help reduce your risk of getting a yeast infection: If youve never had a yeast infection, its best to schedule a visit with your healthcare professional to confirm your symptoms are caused by a yeast infection. Glycerin (also called glycerol) suppositories lubricate and stimulate the bowel. Some folks also like to wear a pad or panty liner to help collect any discharge from the suppository. So, it's important to see your doctor if you have BV and start treatment right away. If you're prone to BV, avoiding douches and scented vaginal products, wearing cotton underwear, and using condoms and dental dams may help prevent infections. But they should use sanitary pads instead of tampons as tampons may absorb some of the medication. Trichomoniasis is an STI caused by the parasite trichomonas vaginalis. It may also be a good idea to avoid receiving oral sex to reduce the risk of your partner ingesting boric acid that may still be present in or around your vagina. For most people, inserting boric acid suppositories into the vagina is considered safe. The effectiveness of these alternative methods is still debated among health care providers. doi:10.1097/OLQ.0b013e3181b08456. Sorry for all the typos, my phone is cray. Although boric acid suppositories are generally safe for adults, minor side effects are possible. Here are some guidelines to follow when inserting your boric acid suppository: The suppository should be inserted at the same time each day. Required fields are marked *. And really, there are different side effects of using boric acid suppositories. With imperfect use, this figure can be as high as 28 percent. Boric acid is particularly effective against yeast infections caused by Candida glabrata. Boric Acid - Can You Use It While on Your Period? The antibiotic may be oral (taken by mouth) or a cream or gel that you put into your vagina. Vaginal yeast infections are also known as candidal vulvovaginitis or candidiasis. Study protocol for a randomized controlled trial. Historically, these needed to be prescribed by a health care practitioner and formulated at a specialty compounding pharmacy for individuals, she explains. Learn the research on tea tree oil and, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Powell A, Ghanem KG, Rogers L, et al. Homeopathic Products. However, you should steer away from this product if you are pregnant or have an open wound. For BV prevention, your doctor may suggest continuing treatment 2-3 times a week. Your healthcare provider may also suggest an entirely different treatment plan based on your individual BV situation. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Douching or having new or multiple partners may increase your risk of BV since these activities can disrupt vaginal bacteria. Just make sure it's OK with your doctor. Microdose Lupron Protocol: 15R/6M/6F, Froze all 6 due to high E2 and P4, FET 1: Jan 22, 2014 of one 4AB blast and one 3BB blast (3 blasts on ice! Boric acid for recurrent vulvovaginal candidiasis: The clinical evidence. When consumed by mouth, boric acid is toxic and can potentially lead to death. Ancobon and other antifungal medications require a prescription. Powell A, et al. It's commonly used in suppository capsule form to treat vaginal problems, specifically vaginal yeast infections. You may use your finger or use the type of applicator that comes with anti-thrush treatments. Dangers Of Boric Acid Suppositories - Are They Dangerous? This treatment worked for 27 out of 30 women, or in 90% of the cases. A 2011 research review looked at 14 studies comparing boric acid with other treatments for recurrent yeast infections. Healthline Media does not provide medical advice, diagnosis, or treatment. These are generally mild and can include: If youre using boric acid suppositories to treat a vaginal infection and experience significant discomfort, stop using them and contact your doctor for other treatment options. A quick internet search may bring up some concern about the safety of boric acid suppositories. A trichomonas infection is usually treated with antibiotics, but drug resistance is an increasing problem. You'll unleash radiant confidence with our simple, clean formula that brings perfect balance back to your vagina. Corradi F, et al. He or she will also probably be able to tell you about the boric acid. Depending on the strength, the medication can often take between 3 and 7 days to clear an existing infection. 8. You can also make your own capsules. They found 14 studies in total two randomized clinical trials, nine case series, and four case reports. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. (2007). She's fine. Can Yogurt Be Used to Treat a Yeast Infection? Does anyone know anymore about this, or about using it while TTC? If you or someone else accidentally swallows a boric acid suppository, call 911 or local emergency services. Learn how we can help Reviewed Mar 10, 2021 Thank Dr. Susan Rhoads agrees 1 thank A 19-year-old female asked: Because boric acid is naturally found in the environment, many people consider it to be a greener option for treating vaginal infections. TTC since December 2011 Me: 29 ovulatory disorder DH: 30 MFI - low everything Boric acid for recurrent vulvovaginal candidiasis: The clinical evidence. In many cases, they may also provide faster and more targeted relief than oral medications, along with fewer side effects. If these are not bothersome, its probably ok Boric acid is a very caustic substance and could cause burns of the penis if it came into contact with the penis. Effect of lactic acid suppositories compared with oral metronidazole and placebo in bacterial vaginosis: a randomised clinical trial. Genitourinary medicine vol. Q: Is it safe to have intercourse after I have inserted the suppository? Intravaginal boric acid (IBA) represents one of the only options available to treat azole-resistant vulvovaginal candidiasis (VVC) and is included as part of multiple national guidelines (including the United Kingdom and the United States) for the treatment of VVC or recurrent bacterial vaginosis. Always consult a health care provider for advice on how much and for how long to use the suppositories. Its available in several forms, including suppositories that you place into your vagina. (2003). Labrie, F., Archer, D. F., Koltun, W., Vachon, A., Young, D., Frenette, L., Moyneur, . (n.d.). In a 2011 research review, researchers evaluated multiple studies revolving around boric acid as a treatment for recurrent vulvovaginal candidiasis. You can shop for premade boric acid suppositories at most drugstores or online. 2021;11:631972. doi:10.3389/fcimb.2021.631972. "My go-to regimen is one suppository (500 to 600 mg) intravaginally once per week for eight to 12 weeks, she says. Make sure to complete the prescribed course of treatment to reduce the likelihood of the infection returning. Boric acid should not be used during pregnancy. To date, one clinical trial has been performed on boric acid for bacterial vaginosis, although others have been proposed. Larsen, B., Petrovic, M., & De Seta, F. (2018, April). It immobilizes and kills the sperm, so they are unable to travel to the womb. Bacterial vaginosis. These come in different strengths and are available for purchase over the counter. i've been using boric acid suppositories for almost 2 weeks and never saw this. To establish that the product manufacturers addressed safety and efficacy standards, we: We do the research so you can find trusted products for your health and wellness. Sex Transm Dis. Some more research has also found that boric acid may help treat infections with Trichomonas vaginalis that are difficult to treat. Boric acid poisoning can lead to serious symptoms and can be fatal. Hi! For many decades, people have used boric acid suppositories as an alternative treatment for recurrent vaginal yeast infections. Keep reading to learn more about this safe and affordable treatment method. Continue reading to learn more about the safety of boric acid suppositories and more. The boric acid has a half life of 12-24 hours. Boric acid can be toxic if ingested or put on open wounds. Are the medications commonly used for the management of yeast infections safe to use during pregnancy? In the 2009 trial, participants were given oral nitroimidazole, an antimicrobial drug used to treat vaginal infections, followed by boric acid suppositories. Boric acid is a white powder derived from the element boron. The probiotic I take are not suppositories, they're oral pills. But are they boric acid suppositories legit and, more importantly, safe? Probiotics for the Treatment of Women with Bacterial Vaginosis. Ovid, Clinical Microbiology & Infection, July 2007, oce.ovid.com/article/00125357-200707000-00002. The small study compared the efficacy of vitamin E suppositories and a vaginal cream, containing the hormone estrogen, among 52 women. Video chat with a U.S. board-certified doctor 24/7 in less than one minute for common issues such as: colds and coughs, stomach symptoms, bladder infections, rashes, and more. Vaginal boric acid will not prevent pregnancy and should not be used as a form of birth control. (2003). Boric acid comes in a suppository form for vaginal use, but research on boric acid for BV is pretty limited. What happens if i used boric acid while pregnant ANSWER Existing data indicate that exposure to oral and topical antifungals, topical antiseptics, or corticosteroids during pregnancy is not associated with increased risk of major malformations. Research suggests that when used appropriately, boric acid suppositories can help reduce the risk of recurrent infections. I'm spotting i'm on birth control so i took boric acid suppositories will that stop the spotting? How Many Bodies Have Been Found In Lake Mead, Celebrities Talk About Being Rich, Due To Operating Conditions Package May Be Delayed Ups, Award Headquarters Po Box 318 Crystal Lake Il, Articles I

Welcome to . This is your first post. Edit or delete it, then start writing!